Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

D002

Sigma-Aldrich

(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide

solid

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
6,7-ADTN hydrobromide
Empirical Formula (Hill Notation):
C10H13NO2 · HBr
CAS Number:
13575-86-5
Molecular Weight:
260.13
MDL number:
MFCD00036982
UNSPSC Code:
12352200
PubChem Substance ID:
24277893

form

solid

storage condition

protect from light

solubility

H2O: >10 mg/mL (Dissolve in oxygen-free water containing 0.1% sodium metabisulfite or other antioxidants.)
aqueous base: unstable

storage temp.

2-8°C

SMILES string

Br[H].NC1CCc2cc(O)c(O)cc2C1

Gene Information

human ... DRD1(1812) , DRD2(1813) , DRD3(1814) , DRD4(1815) , DRD5(1816)

Biochem/physiol Actions

Dopamine receptor agonist.

Caution

Air- and light-sensitive

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Patel et al.
Behavioral neuroscience, 102(4), 596-600 (1988-08-01)
The effects of administration of gamma-aminobutyric acid (GABA) compounds into the ventral pallidum and substantia innominata on the locomotor hyperactivity induced by the dopamine agonist 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN) in the nucleus accumbens were investigated in rats. Hyperactivity induced by ADTN was
M K Boelen et al.
Brain research, 645(1-2), 240-246 (1994-05-09)
The activity of the enkephalin-immunoreactive (ENSLI) amacrine cells of the chicken retina is low in the light and high in the dark, resulting in parallel increases and decreases in the levels of the enkephalins. In vivo, the selective dopaminergic D1
A J Balmforth et al.
Journal of neurochemistry, 51(5), 1510-1515 (1988-11-01)
3,4-Dihydroxyphenylethylamine (dopamine) and beta-adrenergic receptor agonists and antagonists were assessed for their effects on cyclic AMP accumulation in human astrocytoma derived clone D384 cells. Dopamine, SKF 38393, and 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene increased cyclic AMP content with Ka values of 2.0, 0.2, and
U Sreenivasan et al.
Journal of medicinal chemistry, 36(2), 256-263 (1993-01-22)
A series of analogues of the potent analogue of Pro-Leu-Gly-NH2 (PLG), 2-oxo-3(R)-[(2(S)-pyrrolidinylcarbonyl)amino]-1-pyrrolidineacet amide (2) were synthesized in which the (R)-gamma-lactam residue of 2 was replaced with a (R)-beta-lactam, (R)-aminosuccinimide, (R)-cycloseryl, (R)-delta-lactam, (R)-epsilon-lactam, or (S)-epsilon-lactam residue to give analogues 3-8, respectively.
K N Iarygin et al.
Bioorganicheskaia khimiia, 17(9), 1172-1176 (1991-09-01)
The interaction of the tetrahydroisoquinoline (THIQ) and 3-aminotetraline (3-AT derivatives with opioid mu-receptors has been studied. It is shown that THIQ and 3-AT derivatives bind to a site on the mu-receptor which these compounds are likely to share with "classical"
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service