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Merck
CN

C9759

Cardiotoxin from Naja mossambica mossambica

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About This Item

UNSPSC Code:
12352200

Key Documents

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storage temp.

−20°C

Quality Level

200

Other Notes

Snake toxin; mixture of cardiotoxins.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
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Certificates of Analysis (COA)

Lot/Batch Number
023M4065V
023M4064V
013M4102V
013M4103V
031M4091V

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is Product C9759, Cardiotoxin, soluble in?

    Sigma tests the solubility in water at 1 mg/mL; this yields a clear to slightly hazy solution.

  4. What is the molecular weight of Product C9759, Cardiotoxin?

    According to Biochim. Biophys. Acta, 336, 470, (1974), this product is a mixture of cardiotoxins all having a molecular weight of approximately 7,000 Da.

  5. Has this product been tested in any in vivo studies?

    We have not done any bioassay studies with this product in our labs here at Sigma-Aldrich. The following references contain information regarding bioassay studies: Cell Research, 16, 713-722 (2006) and J. Thorac. Cardiovasc. Surg., 121, 871-878 (2001).

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Omar Cortez-Toledo et al.
PloS one, 12(2), e0171268-e0171268 (2017-02-09)
Muscle atrophy is a prevalent condition in illness and aging. Identifying novel pathways that control muscle mass may lead to therapeutic advancement. We previously identified Nur77 as a transcriptional regulator of glycolysis in skeletal muscle. More recently, we showed that
Tuan H N Nguyen et al.
BMC cell biology, 11, 57-57 (2010-07-22)
In normal adult skeletal muscle, cell turnover is very slow. However, after an acute lesion or in chronic pathological conditions, such as primary myopathies, muscle stem cells, called satellite cells, are induced to proliferate, then withdraw definitively from the cell
Mehmet E Yalvac et al.
Skeletal muscle, 7(1), 27-27 (2017-12-16)
Previous studies in patients with limb-girdle muscular dystrophy type 2A (LGMD2A) have suggested that calpain-3 (CAPN3) mutations result in aberrant regeneration in muscle. To gain insight into pathogenesis of aberrant muscle regeneration in LGMD2A, we used a paradigm of cardiotoxin
G Jayaraman et al.
The Journal of biological chemistry, 274(25), 17869-17875 (1999-06-11)
Snake venom cardiotoxins have been recently shown to block the enzymatic activity of phospholipid protein kinase and Na+,K+-ATPase. To understand the molecular basis for the inhibitory effects of cardiotoxin on the action of these enzymes, the nucleotide triphosphate binding ability
Erika Ferrari et al.
Biosensors, 10(9) (2020-09-03)
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced in vitro tools able to replicate essential functions of human organs. Owing to their unprecedented ability to recapitulate key features of the native cellular environments, they represent promising tools
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