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C9357

Sigma-Aldrich

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

≥96% (HPLC), suitable for western blotting and enzyme immunoassays

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Synonym(s):
XJ735
Empirical Formula (Hill Notation):
C23H32N8O7
CAS Number:
153381-95-4
Molecular Weight:
532.55
MDL number:
MFCD11046000
UNSPSC Code:
12352200
PubChem Substance ID:
329775202
NACRES:
NA.26

Quality Level

200

Assay

≥96% (HPLC)

form

powder

technique(s)

enzyme immunoassay: suitable
western blot: suitable

color

white

UniProt accession no.

P01303

storage temp.

−20°C

SMILES string

C[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2

InChI

1S/C23H32N8O7/c1-12-19(35)31-15(6-3-7-26-23(24)25)21(37)28-11-17(32)30-16(9-18(33)34)22(38)27-10-13-4-2-5-14(8-13)20(36)29-12/h2,4-5,8,12,15-16H,3,6-7,9-11H2,1H3,(H,27,38)(H,28,37)(H,29,36)(H,30,32)(H,31,35)(H,33,34)(H4,24,25,26)/t12-,15-,16-/m0/s1

InChI key

HRASXYOWQQTBAQ-RCBQFDQVSA-N

Gene Information

human ... NPY(4852)

Related Categories

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

Biochem/physiol Actions

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.
Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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