C8534
Anti-Chorionic Gonadotropin (α+β subunits) (HCG) antibody produced in rabbit
whole antiserum
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Chorionic Gonadotropin Antibody, HCG Antibody - Anti-Chorionic Gonadotropin (α+β subunits) (HCG) antibody produced in rabbit, Hcg Antibodies, Hcg Antibody
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
species reactivity
human
technique(s)
immunohistochemistry: 1:100 using human placental tissue
radioimmunoassay: 1:50,000
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
General description
Human Chorionic Gonadotropin (HCG) is a hormone detected in the blood and urine during pregnancy. The peak levels of HCG are detected around Week 12 of gestation and diminish during remaining period of pregnancy. HCG is composed of α and β subunits. There are five variants of HCG that have been identified; HCG, hyperglycosylated HCG, sulphated HCG, free β subunit and pituitary HCG. The important functions of HCG include implantation, angiogenesis, progesterone production, regulation of immune cells and cytotrophoblast differentiation and development of placenta
Anti-Chorionic Gonadotropin (α + α subunits) antibody is specific for both α and β subunits of human chorionic gonadotropin.
Anti-Chorionic Gonadotropin (α + α subunits) antibody is specific for both α and β subunits of human chorionic gonadotropin.
Immunogen
HCG
Application
Anti-Chorionic Gonadotropin (α + α subunits) antibody may be used for RIA at a minimum working dilution of 1:50,000. For immunohistochemistry, the recommended working dilution is 1:100-1:200. The antibody was also used for immunofluorescence at a working dilution of 1:50 and for ELISA.
Reconstitution
Dilute with buffer: 0.01 M phosphate, pH 7.8, 0.15 M sodium chloride, 0.5% bovine serum albumin and 0.1 sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Biological functions of hCG and hCG-related molecules
Reproductive Biology and Endocrinology, 8, doi: 10-doi: 10 (2010)
Oncology letters, 16(4), 4271-4278 (2018-09-11)
Hormones and their receptors affect the development process of gastric cancer. Previous studies have revealed that human chorionic gonadotropin (hCG) is expressed in gastric cancer tissue. However, the mechanism by which hCG exerts its effects on gastric cancer cells had
Placenta, 32 Suppl 2, S182-S185 (2011-02-08)
Human chorionic gonadotropin (hCG) is crucial for successful pregnancy. Its many functions include angiogenesis and immune regulation. Despite years of research, the etiology of preeclampsia remains unknown. Marked by insufficient trophoblast invasion and poor spiral artery remodeling, preeclampsia has also
hCG, the wonder of today's science
Reproductive Biology and Endocrinology, 10, doi: 10-doi: 10 (2010)
Analytical biochemistry, 366(2), 175-181 (2007-06-02)
The development of a simultaneous multianalyte immunoassay for the detection of progesterone and human chorionic gonadotropin (hCG) in serum is described. In this simultaneous multianalyte assay, two different enzymes, viz. horse radish peroxidase (HRP) and alkaline phosphatase (ALP), were used
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