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C8484

Sigma-Aldrich

Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone

solid, ≥90% (TLC)

Synonym(s):

Z-AEVD-FMK

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About This Item

Empirical Formula (Hill Notation):
C28H39N4O10F
CAS Number:
1135688-47-9
Molecular Weight:
610.63
MDL number:
MFCD03453601
UNSPSC Code:
12352200
PubChem Substance ID:
329775172
NACRES:
NA.77

Product Name

Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone, solid

Assay

≥90% (TLC)

Quality Level

200

form

solid

color

white

solubility

DMF: soluble

storage temp.

−20°C

SMILES string

COC(=O)CC[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

InChI

1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5)33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10-18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33,38)/t17-,19-,20-,24-/m0/s1

InChI key

CHZRBQFKZDGMTP-CDSYHYPYSA-N

Amino Acid Sequence

Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK

Application

Caspase inhibitor.

Preparation Note

Prepare 20 mM stock solutions in dry DMSO to maintain product stability. Also soluble in DMF.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
036K1679
095K1066
045K1496
093K1430
071K1764

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