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C8056

Sigma-Aldrich

Calf Serum

from formula-fed bovine calves, iron supplemented, USA origin, sterile-filtered, suitable for cell culture

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Synonym(s):
bovine calf sera, bovine calf serum, calf sera, calf serum
MDL number:
MFCD00243108
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

bovine (calf) (formula-fed)

Quality Level

500

sterility

sterile-filtered

form

liquid

composition

hemoglobin, ≤35 mg/dL

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/mL Endotoxin

shipped in

dry ice

storage temp.

−20°C

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Related Categories

Application

Iron-supplemented bovine serum may be used as an alternative to fetal bovine serum in the CHO/HGPRT mutation assay, Oberly, et. al. Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics

Testing Method

Endotoxin tested

Preparation Note

Each lot is supplemented to a constant iron concentration.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Rune Busk Damgaard et al.
EMBO molecular medicine, 11(3) (2019-02-26)
The deubiquitinase OTULIN removes methionine-1 (M1)-linked polyubiquitin signals conjugated by the linear ubiquitin chain assembly complex (LUBAC) and is critical for preventing TNF-driven inflammation in OTULIN-related autoinflammatory syndrome (ORAS). Five ORAS patients have been reported, but how dysregulated M1-linked polyubiquitin
Reza Mirnejad et al.
Microbial pathogenesis, 109, 8-14 (2017-05-17)
Brucella is zoonotic pathogen that induces abortion and sterility in domestic mammals and chronic infections in humans called Malta fever. It is a facultative intracellular potential pathogen with high infectivity. The virulence of Brucella is dependent upon its potential virulence
T J Oberly et al.
Mutation research, 244(2), 105-109 (1990-06-01)
Iron-supplemented bovine calf serum (ICS) was found to be a viable alternative to fetal bovine serum (FBS) in the growth promotion and cloning efficiency of Chinese hamster ovary (CHO) cells that are used in the HGPRT mutation assay. Suspension cultures
D R Dahling et al.
Journal of virological methods, 27(3), 287-294 (1990-03-01)
Two studies comparing sewage-isolated and laboratory stock viruses were conducted to determine if alternative forms of serum or serum extenders could be used in place of fetal bovine serum without a significant loss of viral titer. In the first study
S C Thumma et al.
Cancer gene therapy, 22(8), 396-401 (2015-08-01)
Elevated levels of eukaryotic translation initiation factor 4E (eIF4E) enhance translation of many malignancy-related proteins, such as vascular endothelial growth factor (VEGF), c-Myc and osteopontin. In non-small-cell lung cancer (NSCLC), levels of eIF4E are significantly increased compared with normal lung
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