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Safety Information

C8033

Sigma-Aldrich

Z-Ala-Pro-Leu (dicyclohexylammonium) salt

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About This Item

Empirical Formula (Hill Notation):
C22H31N3O6 · C12H23N
CAS Number:
108321-20-6
Molecular Weight:
614.82
MDL number:
MFCD00057890
UNSPSC Code:
12352209
PubChem Substance ID:
329775157
NACRES:
NA.26

form

solid

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

C1CCC(CC1)NC2CCCCC2.CC(C)C[C@H](NC(=O)[C@@H]3CCCN3C(=O)[C@H](C)NC(=O)OCc4ccccc4)C(O)=O

InChI

1S/C22H31N3O6.C12H23N/c1-14(2)12-17(21(28)29)24-19(26)18-10-7-11-25(18)20(27)15(3)23-22(30)31-13-16-8-5-4-6-9-16;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-6,8-9,14-15,17-18H,7,10-13H2,1-3H3,(H,23,30)(H,24,26)(H,28,29);11-13H,1-10H2/t15-,17-,18-;/m0./s1

InChI key

BPZRECFZFZDXFS-OOAIBONUSA-N

Application

Cbz-Ala-Pro-Leu (Cbz-APL), an N-terminal carboxybenzyl blocked tripeptide, may be use in solid phase peptide synthesis (SPPS).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
030H0085

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Byunghee Yoo et al.
Bioconjugate chemistry, 18(3), 903-911 (2007-03-03)
A versatile method is disclosed for solid-phase peptide synthesis (SPPS) of molecular imaging contrast agents. A DO3A moiety was derivatized to introduce a CBZ-protected amino group and then coupled to a polymeric support. CBZ cleavage with Et2AlCl/thioanisole was optimized for

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