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Merck
CN

C7786

Conalbumin from chicken egg white

suitable for cell culture, BioReagent

Synonym(s):

Ovotransferrin

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About This Item

CAS Number:
1391-06-6
UNSPSC Code:
12352202
EC Number:
215-727-0
NACRES:
NA.75
MDL number:
MFCD00130856

Key Documents

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Product Name

Conalbumin from chicken egg white, suitable for cell culture, BioReagent

biological source

chicken egg white

product line

BioReagent

form

powder

concentration

80-100 % protein Biuret

technique(s)

cell culture | mammalian: suitable

solubility

water: 25 mg/mL, clear to slightly hazy, pink

cation traces

Fe: ≤0.02%

UniProt accession no.

P02789

shipped in

ambient

storage temp.

−20°C

Quality Level

200

Gene Information

chicken ... TF(396241)

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Application

Conalbumin has been used:
  • as a constituent of Leibovitz 15 (L15) medium involved in preparation of primary neuronal cultures
  • to study its adsorption property on a metal surface in the presence of an external electric potential
  • to determine its adsorption isotherms in anion exchange chromatography by multivariate analysis

Biochem/physiol Actions

Conablumin (aka ovotransferrin) is a glycoprotein derived from egg white with a sequence similar to serum transferrin, but with a different glycosylation pattern. It is a strong iron binder with antiviral and antibacterial activities.
Conalbumin facilitates the transport of iron to the developing embryo. It exhibits anti-microbial activity thus, conalbumin is used in various applications such as infant formula ingredient, a food additive, and an antimicrobial agent for enhancing animal health. In addition, it also acts as an antifungal, antiviral, anticancer, antioxidative, antihypertensive and immunoregulatory agent.

General description

Conalbumin, also referred to as ovotransferrin, is encoded by the avian transferrin gene in the oviduct. It is a monomeric glycoprotein consisting of 686 amino acids and is a member of transferrin family. Conalbumin is one among the abundant proteins present in the chicken egg white.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

动植物来源生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000511536
0000511535
0000511535
0000511536
0000468265

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Preparation of anionic polyelectrolyte modified magnetic nanoparticles for rapid and efficient separation of lysozyme from egg white
Chen J, et al.
Journal of Chromatography A, 1388, 43-51 (2015)
Ovotransferrin: Structure, bioactivities, and preparation
Wu J and Acero-Lopez A
Food Research International, 46(2), 480-487 (2012)
Adsorption characteristics of various proteins on a metal surface in the presence of an external electric potential
Htwe Ei, et al.
Colloids and Surfaces. B, Biointerfaces, 166, 262-268 (2018)
İrem Lütfiye Atasoy et al.
Journal of chemical neuroanatomy, 80, 19-26 (2016-12-05)
Intracellular aggregation of hyperphosphorylated tau in neurofibrillary tangles (NFTs) is a major neuropathological hallmark of taupathies such as Alzheimer's disease. Okadaic acid (OKA) is a potent inhibitor of PP2A, leading to abnormal tau phosphorylation. Brain-derived neurotrophic factor (BDNF) is a
Nicholas Field et al.
Journal of chromatography. A, 1510, 13-24 (2017-07-03)
The combination of multi-well plates and automated liquid handling is well suited to the rapid measurement of the adsorption isotherms of proteins. Here, single and binary adsorption isotherms are reported for BSA, ovalbumin and conalbumin on a strong anion exchanger
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