C7527
Choline chloride
BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
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About This Item
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-655-4
Beilstein/REAXYS Number:
3563126
MDL number:
biological source
synthetic (organic)
Quality Level
product line
BioReagent
assay
≥98%
form
crystals
mol wt
Mw 139.62 g/mol
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable
color
white
pH
5.0-6.5 (25 °C, 140 g/L)
mp
302-305 °C (dec.) (lit.)
solubility
H2O: 50 mg/mL
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
General description
Choline chloride is a quaternary ammonium salt and associates with hydrogen bond donors (HBD). It is essential for the vital physiological functions and is used as a nutritional additive. Choline is a source of methyl groups for methyl-transfer reactions.
Choline acetyltransferase substrate
Application
Choline chloride has been used:
- as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells
- for choline standard curve generation for quantifying phospholipase D (PLD) activity
- as a component of slice solution for the dissection of entorhinal-hippocampal brain slices
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Synthesis and characterization of choline chloride based binary mixtures
Abbas Q and Binder L
ECS Transactions, 33(7), 49-59 (2010)
Apoptosis of bovine granulosa cells: Intracellular pathways and differentiation
Carou MC, et al.
Acta Histochemica, 119(5), 462-470 (2017)
Harvie P Portugaliza et al.
Scientific reports, 9(1), 14595-14595 (2019-10-12)
Transmission of malaria parasites from humans to mosquito vectors requires that some asexual parasites differentiate into sexual forms termed gametocytes. The balance between proliferation in the same host and conversion into transmission forms can be altered by the conditions of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C7527-1KG | 04061833512807 |
| C7527-500G | 04061833512920 |
| C7527-100G | 04061833512791 |