C7519
Choline bicarbonate
~80% in H2O
Synonym(s):
2-Hydroxyethyl)trimethylammonium bicarbonate
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About This Item
Linear Formula:
C5H14NO · HCO3
CAS Number:
Molecular Weight:
165.19
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
50501514
MDL number:
InChI
1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1
SMILES string
OC([O-])=O.C[N+](C)(C)CCO
InChI key
DQKGOGJIOHUEGK-UHFFFAOYSA-M
form
liquid
concentration
~80% in H2O
density
1.17 g/mL at 25 °C (lit.)
lipid type
phospholipids
storage temp.
2-8°C
Quality Level
General description
Choline acetyltransferase substrate
Application
Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.
Biochem/physiol Actions
Acyl group acceptor
Other Notes
Note: The bicarbonate converts to the carbonate with release of CO2 on aging.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Louisa G Sylvia et al.
Psychotherapy and psychosomatics, 82(1), 10-19 (2012-11-14)
Pharmacotherapy is the first line of treatment for bipolar disorder, but many patients continue to experience persistent subthreshold symptoms. Alternative adjunct treatments, including nutritional therapies, may have the potential to alleviate residual symptoms and improve the outcomes of standard pharmacotherapy.
Ludmilla R Jorge et al.
Frontiers in pharmacology, 11, 243-243 (2020-05-12)
In this research project, synthesis and characterization of ionic liquids and their subsequent utilization as facilitators of transdermal delivery of human insulin was pursued. Choline geranate and choline oleate ionic liquids (and their deep eutectic solvents) were produced and characterized
Mohit J Mehta et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(5), 1269-1274 (2018-11-07)
Significant research is currently underway to develop environmentally friendly UV-shielding materials. Herein, we have constructed choline citrate (a biobased ionic liquid, IL) stabilized homogeneous gelatin-lignin UV-shielding films with excellent antimicrobial and mechanical properties. The synthesis procedure of the films is
Hussain Mohamad Awwad et al.
Clinical biochemistry, 45(18), 1548-1553 (2012-08-28)
Choline is an essential nutrient that is necessary for cell membrane synthesis and phospholipid metabolism and functions as an important methyl donor. Multiple roles for choline in cancer development have been suggested. Choline can affect DNA methylation and lead to
Erica C Silva et al.
Research in veterinary science, 135, 42-58 (2021-01-14)
In the present research work, we propose a new antimicrobial treatment for pyoderma via cutaneous permeation of bacteriophage particles conveyed in a hydroxyethylcellulose (HEC) gel integrating ionic liquid as a permeation enhancer. Ionic liquids are highly viscous fluids constituted exclusively
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