All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C100H170N38O32S6
CAS Number:
Molecular Weight:
2609.05
UNSPSC Code:
12352200
Recommended Products
Assay
≥90% (HPLC)
form
powder
composition
Peptide content, ~60%
storage temp.
−20°C
Amino Acid Sequence
Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Lys-Lys-Cys-Lys-Asp-Arg-Gln-Cys-Lys-Hyp-Gln-Arg-Cys-Cys-Ala-NH2 [Disulfide Bridges: undefined]
Biochem/physiol Actions
Selective blocker of voltage-dependent Na+ channels which exhibits channel binding kinetics similar to those of tetrodotoxin and saxitoxin, but possesses a >1,000 fold selectivity for muscle versus neuronal Na+ channels; originally isolated from the venom of the marine snail Conus geographus L.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
高风险级别生物产品--毒素类产品
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
F A Meunier et al.
British journal of pharmacology, 121(6), 1224-1230 (1997-07-01)
1. The actions of a chromatographically identified extract of the marine dinoflagellate Ostreopsis lenticularis, named ostreotoxin-3 (OTX-3), were studied on frog isolated neuromuscular preparations. 2. OTX-3 (1-10 microg ml(-1)) applied to cutaneous pectoris nerve-muscle preparations depolarized skeletal muscle fibres and
J A Grimes et al.
Journal of cellular physiology, 175(1), 50-58 (1998-03-10)
Voltage-gated Na+ channels, classically associated with impulse conduction in excitable tissues, are also found in a variety of epithelial cell types where their possible functions are not known so well. We have previously reported expression of a voltage-gated Na+ channel
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service