C7017
Choline chloride
≥99%
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
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About This Item
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
Beilstein:
3563126
EC Number:
MDL number:
UNSPSC Code:
50501514
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
biological source
synthetic
Quality Level
Assay
≥99%
form
powder
color
white
mp
302-305 °C (dec.) (lit.)
lipid type
phospholipids
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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General description
Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.
Application
Choline chloride has been used:
- in choline release assay
- as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
- as a standard to analyse interrelationships between methionine and choline metabolism
Biochem/physiol Actions
Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.
Substrates
Choline acetyltransferase substrate
also commonly purchased with this product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Clinical biochemistry of domestic animals (2008)
Encyclopedia of Food Sciences and Nutrition (Second Edition) (2003)
Rumen-protected choline for dairy cows: the in situ evaluation of a commercial source and literature evaluation of effects on performance and interactions between methionine and choline metabolism
Brusemeister F and Sudekum KH
Animal Research, 55(2), 93-104 (2006)
Pathophysiological roles and clinical importance of biomarkers in acute coronary syndrome
Chan CP and Rainer TH
Advances in Clinical Chemistry, 59, 23-63 (2013)
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