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C6070

Sigma-Aldrich

CAPS

BioXtra, ≥99%

Synonym(s):

3-(Cyclohexylamino)-1-propanesulfonic acid

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About This Item

Linear Formula:
C6H11NH(CH2)3SO3H
CAS Number:
1135-40-6
Molecular Weight:
221.32
Beilstein:
2835588
EC Number:
214-492-1
MDL number:
MFCD00003837
UNSPSC Code:
12161700
PubChem Substance ID:
24892833
NACRES:
NA.25

product line

BioXtra

Quality Level

400

Assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

3.0-7.0 (20 °C, 0.5 M in H2O)

pKa (25 °C)

10.4

pKa 

10.4

mp

>300 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

absorption

≤0.2 at 260 in H2O at 0.5 M
≤0.2 at 280 in H2O at 0.5 M

storage temp.

room temp

SMILES string

OS(=O)(=O)CCCNC1CCCCC1

InChI

1S/C9H19NO3S/c11-14(12,13)8-4-7-10-9-5-2-1-3-6-9/h9-10H,1-8H2,(H,11,12,13)

InChI key

PJWWRFATQTVXHA-UHFFFAOYSA-N

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Application


  • Lignin degradation by a novel thermophilic and alkaline yellow laccase from Chitinophaga sp.: This study highlights the application of CAPS buffer in stabilizing enzymes under extreme conditions for industrial lignin degradation. The use of CAPS enhances the stability and activity of laccase, pivotal for bio-refining processes (Buzzo et al., 2024).

  • Improved Refolding of a Human IgG1 Fc (CH2-CH3) Scaffold from Its Inclusion Body in E. coli by Alkaline Solubilization.: Research demonstrates CAPS buffer′s critical role in the solubilization and refolding of recombinant proteins. This advancement is significant for therapeutic protein production, ensuring higher yield and functionality (Ishikawa et al., 2022).

  • An optimized SDS-PAGE protocol with a new blotting system for the initial testing procedure of ESAs in doping control.: This paper utilizes CAPS buffer in the development of a new SDS-PAGE blotting system for doping tests, offering more reliable and faster detection of erythropoiesis-stimulating agents in sports (Martin et al., 2022).

  • Insight into organophosphate chemical warfare agent simulant hydrolysis in metal-organic frameworks.: The study uses CAPS buffer to investigate the hydrolysis reactions of chemical warfare agents in metal-organic frameworks. This research is crucial for developing materials that can neutralize hazardous agents safely and efficiently (Ploskonka and DeCoste, 2019).

  • Complexometric and argentometric titrations using thread-based analytical devices.: CAPS buffer is applied in novel thread-based analytical devices for environmental monitoring. These devices, utilizing complexometric and argentometric titrations, offer a portable, cost-effective solution for on-site water quality analysis (Jarujamrus et al., 2018).


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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Frances E Lock et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), E3534-E3543 (2014-08-13)
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Children and their parents are at risk of posttraumatic stress disorder (PTSD) following injury due to pediatric accidental trauma. Screening could help predict those at greatest risk and provide an opportunity for monitoring so that early intervention may be provided.
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