C5269
Clindamycin hydrochloride
lincosamide antibiotic
Synonym(s):
(7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin
About This Item
Quality Level
form
crystalline
impurities
≤2 mol/mol EtOH
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI
1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
InChI key
AUODDLQVRAJAJM-XJQDNNTCSA-N
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Related Categories
General description
Application
Biochem/physiol Actions
Other Notes
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Lact. - Skin Sens. 1
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the antibiotic potency of Clindamycin hydrochloride, Product C5269?
We do not include the potency of the compound in our quality specifications. Please contact Sigma-Aldrich Technical Service for the availability of lot-specific potency from our supplier.
What is the pH of an aqueous solution of Clindamycin hydrochloride, Product C5269?
The expected pH of a 100 mg/ml aqueous solution is from 3.0 to 5.5, per USP 31, p. 1796.
You list the purity of Clindamycin hydrochloride, Product C5269, as determined by thin layer chromatography. Is it possible to determine purity by other chromatographic methods?
The USP 31 describes a liquid chromatographic method utilizing Clindamycin Hydrochloride and Lincomycin Hydrochloride standards. Other publications may be searched on PubMed, such as G. La Follette et al., J Chromatogr., Vol. 431 (No. 2), pp. 379-388 (1988).
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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