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Merck
CN

C5132

Carbazole

≥95% purity (GC), powder

Synonym(s):

Dibenzopyrrole; Diphenylenimine

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About This Item

Empirical Formula (Hill Notation):
C12H9N
CAS Number:
86-74-8
Molecular Weight:
167.21
NACRES:
NA.47
PubChem Substance ID:
24892756
UNSPSC Code:
12171500
EC Number:
201-696-0
MDL number:
MFCD00004960
Beilstein/REAXYS Number:
3956

Key Documents

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Product Name

Carbazole, ≥95% (GC)

InChI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

InChI key

UJOBWOGCFQCDNV-UHFFFAOYSA-N

SMILES string

c1ccc2c(c1)[nH]c3ccccc23

vapor pressure

400 mmHg ( 323 °C)

assay

≥95% (GC)

form

powder

technique(s)

titration: suitable

color

white to tan

bp

355 °C (lit.)

mp

243-246 °C (lit.)

solubility

acetone: 50 mg/mL

density

1.1 g/cm3 at 18 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Analysis Note

May contain dark particles.

Application

Carbazole has been used in the uronic acid assay.

Biochem/physiol Actions

Carbazole mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective, and pancreatic lipase suppression activities.

General description

Carbazole is an aromatic heterocyclic organic molecule.

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

428.0 °F - closed cup

flash_point_c

220.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN1607
BCCM1268
BCCK0009
BCCH0891
BCCD0936

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CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
Xiaofeng Liu et al.
Advanced materials (Deerfield Beach, Fla.), 24(33), 4505-4510 (2012-06-22)
An arylated-carbazole conjugated polymer with a deep HOMO level has been developed. Solar cells based on blends of PCX3 and PC(71) BM show efficiency of 3.9% with a V(oc) of 0.96 V. The device performance can be improved to 5.1%
Jae-Min Suk et al.
Organic letters, 14(19), 5018-5021 (2012-09-18)
Chiral organic anions such as camphorsulfonates and cAMP give rise to the preferential formation of a one-handed helix of an indolocarbazole foldamer, thus inducing characteristic circular dichroic (CD) signals. Moreover, the on and off switching of the chiroptical signal can
Guodong Ji et al.
Journal of hazardous materials, 225-226, 1-7 (2012-05-23)
We examined the effects of power and treatment time on the ultrasonically enhanced ozonation of carbazole dissolved in APG(1214) surfactant solutions, including an analysis of the mechanism of OH radical formation, the zeta potential of the colloidal suspension, the influence
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