Skip to Content
Merck
CN

C4767

β-Cyclodextrin

≥97%

Synonym(s):

beta-Cyclodextrin, Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardinger β-Dextrin

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

Empirical Formula (Hill Notation):
C42H70O35
CAS Number:
Molecular Weight:
1134.98
UNSPSC Code:
12352302
NACRES:
NA.22
PubChem Substance ID:
EC Number:
231-493-2
Beilstein/REAXYS Number:
78623
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

β-Cyclodextrin, ≥97%

InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChI key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

assay

≥97%

form

powder

optical activity

[α]20/D +162±3°, c = 1.5% in H2O

mp

290-300 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL

Quality Level

biological source

plant

Looking for similar products? Visit Product Comparison Guide

Application

β-Cyclodextrin is used as a complexing agent in drug delivery because it forms an inclusion complex with a drug molecule. The complex of cyclodextrin increases the aqueous solubility, dissolution rate and bioavailability of poorly water-soluble drugs, which is useful for the delivery of the medical agent to a biological system.

General description

β-Cyclodextrin is a cyclic oligosaccharide consisting of seven glucose subunits joined by α-(1,4) glycosidic bonds forming a truncated conical structure. It is widely used in food, pharmaceutical, cosmetics, and chemicals industries.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Use of dehydrated beta-cyclodextrin as pharmaceutical excipient
Martini A, et al.
Drug Development and Industrial Pharmacy, 20, 2381-2393 (1994)
Cyclodextrins
Kurkov SV and Loftsson T
The International journal of pharmacy practice, 453, 167-180 (2013)
Inclusion complexation of tolbutamide with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin
Veiga F, et al.
Journal of psychosomatic obstetrics and gynaecology, 129, 63-71 (1996)
Preparation and characterization of microparticles of ?-cyclodextrin/glutathione and chitosan/glutathione obtained by spray-drying
Webber V, et al.
Food Research International, 105, 432-439 (2018)
Study to explore the mechanism to form inclusion complexes of beta-cyclodextrin with vitamin molecules
Saha S, et al.
Scientific Reports, 6, 35764-35764 (2016)

Articles

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

很多重要的代谢化合物,例如脂溶性维生素和激素,在水溶液中的溶解度很低。很多技术被用于提高这些化合物在组织培养物、细胞培养物或其他水基应用中的溶解度。

Related Content

Product Information Sheet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service