Skip to Content

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
All Photos(2)

Key Documents

View All Documentation

C4522

Sigma-Aldrich

Cimetidine

Synonym(s):

SKF-92334

Sign Into View Organizational & Contract Pricing

Select a Size

100 μG
CN¥3,981.65

CN¥3,981.65

Estimated to ship onMay 16, 2025Details

Request a Bulk Order
All Photos(2)

Select a Size

Change View
100 μG
CN¥3,981.65

About This Item

Empirical Formula (Hill Notation):
C10H16N6S
CAS Number:
51481-61-9
Molecular Weight:
252.34
EC Number:
257-232-2
MDL number:
MFCD00133296
UNSPSC Code:
12352200
PubChem Substance ID:
24277766
NACRES:
NA.77

CN¥3,981.65

Estimated to ship onMay 16, 2025Details

Request a Bulk Order

form

powder

Quality Level

200

originator

GlaxoSmithKline

storage temp.

2-8°C

SMILES string

CN\C(NC#N)=N\CCSCc1nc[nH]c1C

InChI

1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChI key

AQIXAKUUQRKLND-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243) , CYP1A2(1544) , CYP3A4(1576) , HRH2(3274) , SLC9A2(6549) , SLC9A5(6553)
mouse ... Abcb1a(18671) , Abcb1b(18669)
rat ... Slc9a1(24782) , Slc9a3(24784) , Slc9a5(192215)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

H2 histamine receptor antagonist; I1 imidazoline receptor agonist; anti-ulcer agent. Blocks cancer metastasis by inhibiting the expression of E-selectin on the surface of endothelial cells, thus blocking tumor cell adhesion.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    WXBF4105V
    BCCG8282
    BCCC3082
    BCBT1578
    BCBP2916V

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    K Kobayashi et al.
    Cancer research, 60(14), 3978-3984 (2000-08-05)
    Although the beneficial effect of cimetidine on survival in cancer has been clinically demonstrated in colorectal cancer patients, the mode of action of cimetidine has not been elucidated. In this report, we have demonstrated for the first time that cimetidine
    Sarit Pal et al.
    Biology open, 11(7) (2022-07-02)
    Histamine exerts its physiological functions through its four receptor subtypes. In this work, we report the subcellular localization of histamine receptor 2 (H2R), a G protein-coupled receptor (GPCR), which is expressed in a wide variety of cell and tissue types.
    H van der Goot et al.
    European journal of medicinal chemistry, 35(1), 5-20 (2000-03-25)
    In this review the histaminergic ligands for the histamine H(1), H(2) and H(3) receptors, which are currently used as tools in pharmacological studies, are described. To study interactions with the histamine H(1) receptor, the H(1) agonist 2-aminoethylthiazole has long since
    Huan Yang et al.
    Molecular medicine (Cambridge, Mass.), 28(1), 57-57 (2022-05-17)
    Severe COVID-19 is characterized by pro-inflammatory cytokine release syndrome (cytokine storm) which causes high morbidity and mortality. Recent observational and clinical studies suggest famotidine, a histamine 2 receptor (H2R) antagonist widely used to treat gastroesophageal reflux disease, attenuates the clinical
    Hiroki Shimizu et al.
    ChemMedChem, 17(16), e202200204-e202200204 (2022-06-14)
    We synthesized and experimentally tested the passive permeability of more than thirty tetrapeptides mimicking the N-terminus of the pro-apoptotic protein Smac (Second mitochondria-derived activator of caspases). Each peptide bore one or two unnatural Hydrogen Bond Acceptor-bearing Amino Acid (HBA-AA) residues
    View All Related Papers

    Articles

    Discover Bioactive Small Molecules for ADME/Tox

    Discover Bioactive Small Molecules for ADME/Tox

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service