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C4479

Sigma-Aldrich

9-Cyclopentyladenine monomethanesulfonate

≥98% (HPLC)

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Synonym(s):
9-CP-Ade mesylate, 9-Cyclopentyladenine mesylate
Linear Formula:
C10H13N5 · CH3SO3H
CAS Number:
189639-09-6
Molecular Weight:
299.35
MDL number:
MFCD11045955
UNSPSC Code:
41106305
PubChem Substance ID:
24278313
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

mp

180-183 °C (lit.)

solubility

H2O: 5 mg/mL, clear

storage temp.

room temp

SMILES string

CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3

InChI

1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)

InChI key

AJMDRSJHCYQPQI-UHFFFAOYSA-N

Biochem/physiol Actions

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical

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