C3633
Cystathionine
≥90% (HPLC)
Synonym(s):
DL,DL-allo-Cystathionine, S-(2-Amino-2-carboxyethyl)homocysteine
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About This Item
Linear Formula:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
CAS Number:
Molecular Weight:
222.26
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Product Name
Cystathionine, ≥90% (HPLC)
Quality Level
Assay
≥90% (HPLC)
form
powder
color
white to off-white
mp
281 °C (dec.)
storage temp.
2-8°C
SMILES string
NC(CCSCC(N)C(O)=O)C(O)=O
InChI
1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
InChI key
ILRYLPWNYFXEMH-UHFFFAOYSA-N
Gene Information
human ... BHMT(635)
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Biochem/physiol Actions
Cystathionine is an intermediate in the biosynthesis of the amino acid cysteine. Cystathionine is used as a substrate to differentiate and analyze cystathionine gamma-lyase(s).
Preparation Note
Prepared by method of Stekol.
Other Notes
A mixture of 4 stereoisomers; L-, D-, L-allo- and D-allo-cystathionine.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
Ruben Esse et al.
International journal of molecular sciences, 20(4) (2019-02-20)
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the metabolism of the essential amino acid methionine. Hcy is considered a risk factor for atherosclerosis and cardiovascular disease (CVD), but the molecular basis of these associations remains elusive. The
Shuai Yuan et al.
Antioxidants & redox signaling, 27(10), 634-653 (2017-04-12)
Hydrogen sulfide (H In light of the recent understanding of oxidized sulfide metabolite formation and reactivity, comparatively few studies have been reported comparing cellular biological and in vivo effects of H Additional studies regarding persulfide and polysulfide formation and molecular
Xu Cao et al.
Antioxidants & redox signaling, 31(1), 1-38 (2018-05-24)
Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous transmitter alongside nitric oxide and carbon monoxide. In
Qinghai Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(6), 2200-2213 (2018-09-27)
The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular endothelial cell dysfunction. Hydrogen sulfide (H2S) has been shown to have an anti-oxidative effect, but its mode
Miriam M Cortese-Krott et al.
Antioxidants & redox signaling, 27(10), 684-712 (2017-04-12)
Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances:
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