C3011
Cesium chloride
Grade I, ≥99.0%
Synonym(s):
Caesium monochloride, Cesium chloride
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About This Item
type
Grade I
Quality Level
Assay
≥99.0%
form
powder
mp
645 °C (lit.)
absorption
≤0.2 at 280 in H2O at 50%
application(s)
hematology
histology
SMILES string
[Cl-].[Cs+]
InChI
1S/ClH.Cs/h1H;/q;+1/p-1
InChI key
AIYUHDOJVYHVIT-UHFFFAOYSA-M
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Application
Cesium chloride has been used as a component of pipette solution, to record mechanosensitive currents in dorsal root ganglia neurons. It has been used in patch clamping to study neurons in intact myenteric ganglia.
Used for the preparation of electrically conducting glasses.Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.
Biochem/physiol Actions
Oral intake of cesium chloride is known to increase the pH in cancer cells. Mild toxicity of cesium chloride might cause hypotension, gastrointestinal distress, numbness and syncope. It also leads to severe hypokalemia, hypomagnesemia, acute heart attack and polymorphic ventricular tachycardia in episodes.
Quality
Solutions may contain a slight haze.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 2
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator
Nature Protocols, 6(7), 979-979 (2011)
Patch clamp recording from enteric neurons in situ
Nature Protocols, 6(1), 15-15 (2011)
Biological trace element research, 135(1-3), 1-9 (2009-08-06)
The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However
Nature communications, 11(1), 3208-3208 (2020-06-27)
Inner hair cells (IHCs) are the primary receptors for hearing. They are housed in the cochlea and convey sound information to the brain via synapses with the auditory nerve. IHCs have been thought to be electrically and metabolically independent from
Langmuir : the ACS journal of surfaces and colloids, 28(2), 1256-1266 (2011-12-14)
All-atom molecular dynamics simulations were conducted to study the dynamics of aqueous electrolyte solutions confined in slit-shaped silica nanopores of various degrees of protonation. Five degrees of protonation were prepared by randomly removing surface hydrogen atoms from fully protonated crystalline
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