C216
Calciseptine from Dendroaspis polylepis polylepis (black mamba)
>98%, amorphous powder
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C299H468N90O87S10
CAS Number:
Molecular Weight:
7036.12
MDL number:
UNSPSC Code:
12352200
Recommended Products
Assay
>98%
form
amorphous powder
storage temp.
−20°C
Looking for similar products? Visit Product Comparison Guide
Amino Acid Sequence
Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys [Disulfide bridges: 3—22, 17—39, 41—52, 53—58]
Biochem/physiol Actions
Selective L-type Ca2+ channel blocker; from the venom of the black mamba Dendroaspis polylepis polylepis.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
O Yasuda et al.
Biochemical and biophysical research communications, 194(2), 587-594 (1993-07-30)
Calciseptine (CaS) is a natural peptidic L-type Ca2+ channel blocker consisting of 60 amino acids with four disulfide bonds. The effects of synthetic CaS on the binding of various ligands to Ca2+ channels of rat brain synaptosomal membranes were studied.
J R de Weille et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(6), 2437-2440 (1991-03-15)
The venom of the black mamba contains a 60-amino acid peptide called calciseptine. The peptide has been fully sequenced. It is a smooth muscle relaxant and an inhibitor of cardiac contractions. Its physiological action resembles that of drugs, such as
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service