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Merck
CN

C2152

Coprostan-3-one

Synonym(s):

3-Keto-5β-cholestane, 5β-Cholestan-3-one

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About This Item

Empirical Formula (Hill Notation):
C27H46O
CAS Number:
Molecular Weight:
386.65
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
210-003-0
MDL number:
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SMILES string

CC(C)CCC[C@H](C)C1CCC2C3CCC4CC(=O)CCC4(C)C3CCC12C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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W F Lau et al.
Biochemistry and molecular biology international, 35(6), 1349-1358 (1995-05-01)
Cholesterol-derived oxysterols such as cholestanol, cholestanone and coprostanone were able to potentiate epinephrine-induced lipolysis in intact rat adipocytes but not cholesterol. The relative potency of the oxysterols followed the sequence: cholestanone > or = coprostanone > cholestanol. Cholestanone was selected
G E Mott et al.
Journal of lipid research, 21(4), 480-484 (1980-05-01)
After oral administration of a mixture of [1,2(n)-3H]cholesterol and [4-14C]cholesterol to a baboon, fecal coprostanone had a 46% lower 3H/14C ratio than the dose administered. Loss of 3H by enolization of the 3-ketone could account for the decrease in 3H/14C.
G V Vahouny et al.
The Journal of nutrition, 117(12), 2009-2015 (1987-12-01)
Young adult rats were fed ad libitum for 4 wk on defined diets containing either no fiber, 10% levels of insoluble fiber sources [cellulose, wheat bran, alfalfa, mixed fibers (Fibyrax)], 5% levels of soluble fiber sources [pectin, guar gum, psyllium
Gerhard Dongowski et al.
The Journal of nutritional biochemistry, 15(4), 196-205 (2004-04-08)
We investigated the effects of pectin with different degrees of methylation (34.5, 70.8, and 92.6%, respectively) on the composition and concentration of intestinal and fecal bile acids and neutral sterols in conventional and germfree rats. Diets containing 6.5% pectin (galacturonan)
E Kim et al.
Annals of nutrition & metabolism, 45(4), 152-158 (2001-07-21)
Currently, there is a growing need for food irradiation that is effective in food preservation and quality improvement. Accordingly, this study was designed to observe the effects of gamma-irradiated dietary fat on plasma lipid concentrations and hepatic cholesterol metabolism in

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