All Photos(3)
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
Beilstein:
3563126
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
synthetic
Quality Level
Assay
≥98%
form
powder or crystals
technique(s)
cell culture | mammalian: suitable
color
colorless to white
mp
302-305 °C (dec.) (lit.)
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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General description
Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.
Application
Choline chloride has been used:
- as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements
- as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP
- as a component of perfusate solution for studying arterial pressure in jejunum samples
Biochem/physiol Actions
Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels. It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.
Substrates
Choline acetyltransferase substrate
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Cytochrome c oxidase inhibition by calcium at physiological ionic composition of the medium: Implications for physiological significance of the effect
Vygodina T, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1858(12), 982-990 (2017)
Effect of choline chloride on the lipid content and composition in the leaves of principal magnetically-oriented radish types
Novitskaya GV, et al.
Russian Journal of Plant Physiology, 51(3), 361-371 (2004)
Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
Chandler TL and White HM
PLoS ONE, 12(2), e0171080-e0171080 (2017)
Evaluation of polyherbal formulation and synthetic choline chloride on choline deficiency model in broilers: implications on zootechnical parameters, serum biochemistry and liver histopathology
Selvam R, et al.
Asian-Australasian Journal of Animal Sciences, 31(11), 1795-1795 (2018)
An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat
Lucas ML and Morrison JD
Physiological Reports, 3(5) (2015)
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