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C1629

Choline bitartrate

Name: Choline bitartrate
Brand: SIGMA

Synonym(s):

2-(Hydroxyethyl)trimethylammonium bitartrate

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₉NO₇

CAS Number:

87-67-2

Molecular Weight:

253.25

EC Number:

201-763-4

UNSPSC Code:

12352200

PubChem Substance ID:

24892428

NACRES:

NA.77

form

powder

Quality Level

200

SMILES string

[O-]C([C@H](O)[C@@H](O)C(O)=O)=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1

InChI key

QWJSAWXRUVVRLH-LREBCSMRSA-M

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Application

Choline bitartrate has been used as one of the components in experimental diets to study the effects on reproductive processes and on bone genes during gestation and lactation.

Biochem/physiol Actions

Choline bitartrate is known to serve as a dietary supplement. Choline acts as a precursor for acetylcholine synthesis.

Acyl group acceptor

Substrates

Choline acetyltransferase substrate

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The effects of choline supplementation in mothers with hypothyroidism on the alteration of cognitive-behavioral, long-term potentiation, morphology, and apoptosis in the hippocampus of pre-pubertal offspring rats.

Siamak Sheikhi et al.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 84(2), 109-121 (2024-02-05)

The mother's thyroid hormone status during gestation and the first few months after delivery can play a crucial role in maturation during the brain development of the child. Transient abnormalities in thyroid function at birth indicate developmental and cognitive disorders

Effects of Diets Enriched in Omega-9 or Omega-6 Fatty Acids on Reproductive Process

Mousavi SN, et al.

Journal of family & reproductive health, 10(2), 85-85 (2016)

Extra virgin olive oil in maternal diet increases osteogenic genes expression, but high amounts have deleterious effects on bones in mice offspring at adolescence

Mousavi SN, et al.

Iranian Journal of Basic Medical Sciences, 19(12), 1299-1299 (2016)

Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1.

Margaret A Mouat et al.

Cells, 11(11) (2022-06-11)

Understanding the neurogenic causes of obesity may reveal novel drug targets to counter the obesity crisis and associated sequelae. Here, we investigate whether the deletion of GPR37L1, an astrocyte-specific orphan G protein-coupled receptor, affects whole-body energy homeostasis in mice. We

No acute effects of choline bitartrate food supplements on memory in healthy, young, human adults

Lippelt DP, et al.

PLoS ONE, 11(6), e0157714-e0157714 (2016)

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