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Key Documents

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C1506

Sigma-Aldrich

Cytidine 5′-triphosphate disodium salt

≥95%

Synonym(s):

CTP

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5 EA
CN¥768.14

CN¥768.14

Estimated to ship onMay 23, 2025Details

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CN¥768.14

About This Item

Empirical Formula (Hill Notation):
C9H14N3Na2O14P3
CAS Number:
36051-68-0
Molecular Weight:
527.12
EC Number:
252-849-3
MDL number:
MFCD00078193
UNSPSC Code:
41106305
PubChem Substance ID:
24892417
NACRES:
NA.77

CN¥768.14

Estimated to ship onMay 23, 2025Details

Request a Bulk Order

Quality Level

200

Assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

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specific activity

~50 U/mg

specific activity

≥1,500 units/mg protein (biuret)

specific activity

300-1,500 units/mg protein

specific activity

1,000-3,000 units/mg protein

form

powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

color

yellow-brown

color

-

color

-

color

-

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

General description

Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.[1]

Application

Cytidine 5′-triphosphate disodium salt has been used:
  • for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis[2]
  • in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis[3]
  • to perform in vitro transcription[4]

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis.[1] Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.[5]
P2X4 purinergic receptor agonist.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    WXBF2785V
    WXBF4387V
    BCCH0293
    BCCJ5953
    BCCF1761

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    Determining structures of RNA aptamers and riboswitches by X-ray crystallography
    Nucleosides, nucleotides & nucleic acids, 135-163 (2009)
    Reversibly constraining spliceosome-substrate complexes by engineering disulfide crosslinks
    McCarthy P, et al.
    Methods, 125, 25-35 (2017)
    Andrea L Edwards et al.
    Methods in molecular biology (Clifton, N.J.), 535, 135-163 (2009-04-21)
    Structural biology plays a central role in gaining a full understanding of the myriad roles of RNA in biology. In recent years, innovative approaches in RNA purification and crystallographic methods have lead to the visualization of an increasing number of
    Secretion From Dense Granules
    Platelets and megakaryocytes, 83-93 (2004)
    Genetics (2016)
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