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biological source
algae (red)
Quality Level
description
Predominantly κ and lesser amounts of λ carrageenan
form
powder
color
white to light brown
useful pH range
7.5-10.5 (1.5% in water)
cation traces
Ca: <3.5%
K: <11%
Na: <2.0%
suitability
suitable for gel preparation
storage temp.
room temp
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General description
Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.
Application
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ- carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities. Carrageenan may be used in the development of biomaterials such as bone graft substitutes; entrapping vessels such as biobeads and encapsulation vehicles for drug delivery. Carrageenan be used to develop hydrogels.
Preparation Note
Blended from various seaweeds to produce rigid gels.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
植物油/植物胶产品
Certificates of Analysis (COA)
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José A Fernández-Romero et al.
Antimicrobial agents and chemotherapy, 56(1), 358-368 (2011-11-09)
Topical microbicides that block the sexual transmission of HIV and herpes simplex virus 2 (HSV-2) are desperately needed to reduce the incidence of HIV infections worldwide. Previously we completed phase 3 testing of the carrageenan-based gel Carraguard. Although the trial
Ahu Uraz et al.
Journal of clinical and experimental dentistry, 5(1), e23-e29 (2014-01-24)
The objective of this study was to histologically and histomorphometrically evaluate the efficacy of the new formulations of eggshell-derived calcium carbonate in rats. The study was conducted on 30 adult male rats. Four standardized and circular intrabony defects were created
Immunopharmacology of the macrophage-toxic agent carrageenan.
A W Thomson et al.
International journal of immunopharmacology, 1(4), 247-261 (1979-01-01)
A W Thomson
Biomedicine / [publiee pour l'A.A.I.C.I.G.], 28(3), 148-152 (1978-05-01)
Since the biological effects of carrageenan were reviewed in 1972 by Di Rosa it has become clear from a large number of reports that this algal polysaccharide markedly influences immune responses. Profound suppression of immunity evidenced by impaired antibody production
S Nicklin et al.
Food additives and contaminants, 6(4), 425-436 (1989-10-01)
Carrageenans are a group of high molecular weight sulphated polygalactans which find extensive use in the food industry as thickening, gelling and protein-suspending agents. Although there is no evidence to suggest that the persorption of small amounts of carrageenans across
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