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B9936

Sigma-Aldrich

Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt

≥97% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):
C34H50N8O10
CAS Number:
65147-06-0
Molecular Weight:
730.81
UNSPSC Code:
12352204
NACRES:
NA.32

product name

Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt, ≥97% (HPLC)

Quality Level

200

Assay

≥97% (HPLC)

form

powder

solubility

methanol: 2 mg/mL, clear, colorless

storage temp.

−20°C

InChI

1S/C34H50N8O10/c1-7-18(2)28(42-33(50)52-34(4,5)6)31(49)40-23(12-13-26(44)45)29(47)38-17-25(43)41-30(48)22(9-8-14-37-32(35)36)39-20-10-11-21-19(3)15-27(46)51-24(21)16-20/h10-11,15-16,18,22-23,28,39H,7-9,12-14,17H2,1-6H3,(H,38,47)(H,40,49)(H,42,50)(H,44,45)(H4,35,36,37)(H,41,43,48)

InChI key

PWOIMWXLMWHALO-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

A sensitive and specific fluorogenic substrate for factor Xa.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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The use of fluorogenic peptide substrates for the detection of coagulation factors II and X after electrophoresis.
P G Board
Annals of human genetics, 46(Pt 4), 293-298 (1982-10-01)
T Morita et al.
Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)
Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were

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