B6403
Botulinum Toxin B solution from Clostridium botulinum
shipped in
dry ice
storage temp.
−20°C
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Biochem/physiol Actions
Inhibits release of catecholamines from adrenal medulla, acetylcholine at neuromuscular junctions.
Neurotoxin that inhibits release of catecholamines from adrenal medulla; blocks release of acetylcholine at neuromuscular junctions.
Physical form
Supplied as ~1 mg/mL in 0.2 M sodium chloride and 0.05 M sodium acetate, pH 6.0.
Regulatory Information
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E López-Alonso et al.
Neuroscience letters, 196(1-2), 37-40 (1995-08-18)
Giant liposomes were made from a mixture of asolectin phospholipid vesicles and presynaptic plasma membranes isolated from Torpedo cholinergic nerve endings. Acetylcholine filled giant liposomes were able to release neurotransmitter upon stimulation by the Ca2+ ionophore A23187 and Ca2+. Botulinum
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