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B5768

Sigma-Aldrich

Biotin 4-amidobenzoic acid sodium salt

≥95%

Synonym(s):

N-(+)-Biotinyl-4-aminobenzoic acid sodium salt, N-Biotinyl-p-aminobenzoic acid sodium salt, Sodium N-(+)-biotinyl-4-aminobenzoate

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About This Item

Empirical Formula (Hill Notation):
C17H20N3NaO4S
CAS Number:
102418-74-6
Molecular Weight:
385.41
MDL number:
MFCD00063374
UNSPSC Code:
12352203
PubChem Substance ID:
24891859
NACRES:
NA.46

Quality Level

200

Assay

≥95%

form

powder

storage temp.

2-8°C

SMILES string

[Na+].[H][C@]12CS[C@@H](CCCCC(=O)Nc3ccc(cc3)C([O-])=O)[C@@]1([H])NC(=O)N2

InChI

1S/C17H21N3O4S.Na/c21-14(18-11-7-5-10(6-8-11)16(22)23)4-2-1-3-13-15-12(9-25-13)19-17(24)20-15;/h5-8,12-13,15H,1-4,9H2,(H,18,21)(H,22,23)(H2,19,20,24);/q;+1/p-1/t12-,13-,15-;/m0./s1

InChI key

AMXZKFYBAOWERX-HZPCBCDKSA-M

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General description

Biotin 4-amidobenzoic acid is a substrate of biotinidase.

Application

Biotin 4-amidobenzoic acid sodium salt has been used as a biotin amide substrate to measure biotinyl-6-aminoquinoline (BAQ) hydrolysis by competitive inhibition.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

related product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Kou Hayakawa et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 240-250 (2006-08-01)
Enzyme kinetic parameters, such as K(m), V(max) (or V), k(cat)/K(m), and K(i) (by biotin or lipoic acid) for biotinidase and lipoamidase were determined in Lewis (LEW) rat and Lactobacillus casei (Shirota) using fluorimetric high-performance liquid chromatography (HPLC). It was found
Laboratory diagnosis of biotinidase deficiency, 2017 update: a technical standard and guideline of the American College of Medical Genetics and Genomics
Strovel ET, et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 19(10) (2017)

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