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Merck
CN

B5154

Betaine monohydrate

new

suitable for cell culture

Synonym(s):

Betaine monohydrate

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About This Item

Linear Formula:
(CH3)3N+CH2COO- · H2O
CAS Number:
Molecular Weight:
135.16
Beilstein:
3626258
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.79
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form

(Powder to crystal)

Quality Level

technique(s)

cell culture | mammalian: suitable

solubility

soluble (50mg/ml)

storage temp.

2-8°C

SMILES string

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2

InChI key

NJZRLXNBGZBREL-UHFFFAOYSA-N

General description

Betaine is a zwitterionic quaternary ammonium compound and is mainly present in animals, microorganisms and plants. It is one of the main constituent of several food items like wheat, shellfish, spinach and sugar beets. It is also termed as trimethylglycine, lycine, glycine betaine and oxyneurine. Betaine is a methyl derivative of glycine.

Application

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.Betaine in culture medium can effectively reduce the level of ROS.

Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Features and Benefits

Betaine is a modified amino acid consisting of glycine with three methyl groups serving as methyl donor for various metabolic pathways.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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