B5057
7-Benzyloxy-4-trifluoromethylcoumarin
≥99% (HPLC), solid
Synonym(s):
7-BFC
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C17H11F3O3
Molecular Weight:
320.26
MDL number:
UNSPSC Code:
12161501
PubChem Substance ID:
NACRES:
NA.47
Recommended Products
Product Name
7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid
Quality Level
Assay
≥99% (HPLC)
form
solid
storage temp.
−20°C
SMILES string
FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12
InChI
1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2
InChI key
WVKLERKKJXUPIK-UHFFFAOYSA-N
Gene Information
rat ... Maoa(29253) , Maob(25750)
Application
7-Benzyloxy-4-trifluoromethylcoumarin has been used:
- in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
- in O-dealkylation reaction to determine the activity of CYP3A
- to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)
Biochem/physiol Actions
Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.
Legal Information
Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Jiannan Ding et al.
Chemosphere, 148, 21-31 (2016-01-23)
The aim of this study was to evaluate the interactive effects of fluoxetine (FLU), roxithromycin (ROX) and propranolol (PRP) on the bioaccumulation and biochemical responses in the crucian carp Carassius auratus. After 7 days of binary exposure (ROX + FLU
Manami Nishiwaki et al.
Scientific reports, 10(1), 17503-17503 (2020-10-17)
Hepatocytes are an important tool for in vitro toxicology testing. In addition to primary cultures, a limited number of immortalized cell lines have been developed. We here describe a new cell line, designated as HepaMN, which has been established from
Vamshi K Manda et al.
Phytotherapy research : PTR, 31(12), 1935-1945 (2017-10-27)
Kratom (Mitragyna speciosa), a native herb of Southeast Asia, is widely known for its psychoactive properties. Recent increase in the use of kratom as a recreational drug has increased the risk of its interaction with conventional drugs if taken concomitantly.
Jiannan Ding et al.
Environmental pollution (Barking, Essex : 1987), 238, 1-9 (2018-03-13)
While the presence of microplastics (MPs) in marine environments has been detected worldwide, the importance of MPs pollution in freshwater environments has also been emphasized in recent years. However, the body of knowledge regarding the biological effects of MPs on
Elias M Oziolor et al.
Ecotoxicology (London, England), 26(6), 809-819 (2017-06-08)
There is increasing interest in quantifying the exposure and effects of anthropogenic contaminants in fish. Determination of exposures in wild fish is routinely performed, but methods to investigate potential effects are less established. One of the most relevant approaches would
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service