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Safety Information

B2377

Sigma-Aldrich

N-Bromoacetamide

powder

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Synonym(s):
NBA
Linear Formula:
CH3CONHBr
CAS Number:
Molecular Weight:
137.96
Beilstein:
969346
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

form

powder

color

white to off-white

mp

105 °C

solubility

water: 100 mg/mL

storage temp.

−20°C

SMILES string

CC(=O)NBr

InChI

1S/C2H4BrNO/c1-2(5)4-3/h1H3,(H,4,5)

InChI key

VBTQNRFWXBXZQR-UHFFFAOYSA-N

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Application

Abolishes the rapid inactivation of membrane sodium- and potassium-ion channels.

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Gongyu Li et al.
Nature communications, 10(1), 4697-4697 (2019-10-18)
Comprehensive protein identification and concomitant structural probing of proteins are of great biological significance. However, this is challenging to accomplish simultaneously in one confined space. Here, we develop a nanosecond photochemical reaction (nsPCR)-based click chemistry, capable of structural probing of
D R Matteson et al.
Biophysical journal, 53(4), 641-645 (1988-04-01)
The whole-cell variation of the patch clamp technique was used to study macroscopic K current in voltage clamped GH3 cells. An inactivating, voltage-dependent K current was studied in isolation by inhibiting Ca-activated K currents with internal Ca chelators and external
Joana Revez et al.
PloS one, 6(10), e26880-e26880 (2011-11-01)
Campylobacter jejuni is the major cause of human bacterial gastroenteritis worldwide, and in a minority of cases, post-infectious complications may occur. ST-22 complex (usually Penner serotype 19) strains have been overrepresented among patients with postinfectious complications of campylobacteriosis. We here
Young Jin Kim et al.
Physical chemistry chemical physics : PCCP, 19(3), 2168-2174 (2017-01-04)
Cu(i)-Containing room temperature ionic liquids (Cu-EnA), prepared from CuCl and ether-functionalized ionic liquids (ILs) bearing a methanesulfonate anion (EnA, n = 1, 2 or 3), were thermally stable and highly effective for the removal of alkynes such as isopropenylacetylene (IPA)
J Tanguy et al.
The Journal of general physiology, 97(3), 499-519 (1991-03-01)
The state dependence of Na channel modification by batrachotoxin (BTX) was investigated in voltage-clamped and internally perfused squid giant axons before (control axons) and after the pharmacological removal of the fast inactivation by pronase, chloramine-T, or NBA (pretreated axons). In

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