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Safety Information

AV48540

Sigma-Aldrich

Anti-TKT antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-FLJ34765, Anti-TKT1, Anti-Transketolase (Wernicke-Korsakoff syndrome)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

68 kDa

species reactivity

mouse, human, bovine, rabbit, rat, pig

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TKT(7086)

General description

TKT codes for transketolase which is involved in directing excess sugar phosphates to glycolytic pathways. Studies in mice have shown that oxidative stress may modulate TKT gene regulation in cornea.
Rabbit Anti-TKT antibody regulates human, mouse, rat, pig, zebrafish, and bovine TKT.

Immunogen

Synthetic peptide directed towards the N terminal region of human TKT

Application

Rabbit Anti-TKT antibody is suitable for western blot applications at a concentration of 1μg/ml.

Biochem/physiol Actions

TKT belongs to the transketolase family. TKT has been implicated in the latent genetic disease Wernicke-Korsakoff syndrome (WKS), which causes specific brain damage.

Sequence

Synthetic peptide located within the following region: ESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVL

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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C Salamon et al.
Genomics, 48(2), 209-220 (1998-04-02)
The transketolase (TKT) gene is expressed 30-50 times more highly in the mature mouse cornea than in other tissues. Here, we have cloned and characterized the 30- to 40-kb single-copy mouse TKT gene. Sequence analysis supports the suggestion that present-day

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