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Merck
CN

AV48166

Anti-EEF1A1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Synonym(s):

Anti-CCS-3, Anti-CCS3, Anti-EEF-1, Anti-EEF1A, Anti-EF-Tu, Anti-EF1A, Anti-Eukaryotic translation elongation factor 1 α 1, Anti-FLJ25721

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

50 kDa

species reactivity

pig, rat, mouse, rabbit, horse, human, canine

technique(s)

western blot: suitable

immunogen sequence

SGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKA

NCBI accession no.

NP_001393

UniProt accession no.

P68104

storage temp.

−20°C

Gene Information

human ... EEF1A1(1915)

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General description

Eukaryotic translation elongation factor 1 α 1 (EEF1A1) regulates the transport of aminoacyl tRNA to the ribosome. Downreguation of eEF1A1 is known to induce cell death in tetraploids. Studies have reported that EEF1A1 functions as a target for the male contraceptive, gamendazole, in rat sertoli cells.
Rabbit Anti-EEF1A1 antibody recognizes chicken, canine, pig, human, mouse, and rat EEF1A1.

Immunogen

synthetic peptide corresponding to a region of human EEF1A1 with an internal ID of P28675

Application

Rabbit Anti-EEF1A1 antibody is suitable for western blot applications at a concentration of 2.5μg/ml.

Physical form

Lyophilized from PBS buffer with 2% sucrose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC18064

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Joseph S Tash et al.
Biology of reproduction, 78(6), 1139-1152 (2008-01-26)
Gamendazole was recently identified as an orally active antispermatogenic compound with antifertility effects. The cellular mechanism(s) through which these effects occur and the molecular target(s) of gamendazole action are currently unknown. Gamendazole was recently designed as a potent orally active
Y Kobayashi et al.
Cell death and differentiation, 16(1), 139-150 (2008-09-30)
When duplicated sister chromatids are not properly compacted in mitosis, chromosomes are mis-segregated, inducing genetically unstable tetraploidy known to facilitate aneuploid malignancies. Here, we show that tetraploid cells produced by impaired chromosomal condensation are eliminated by a novel type of

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