AV44083
Anti-SLC5A11 antibody produced in rabbit
affinity isolated antibody
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Synonym(s):
Anti-KST1, Anti-RKST1, Anti-SGLT6, Anti-SMIT2, Anti-Solute carrier family 5 (sodium/glucose cotransporter), member 11
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
74 kDa
species reactivity
horse, mouse, goat, human, guinea pig, rat, bovine, rabbit, dog
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SLC5A11(115584)
Immunogen
Synthetic peptide directed towards the middle region of human SLC5A11
Application
Anti-SLC5A11 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
SLC5A11 is a sodium/glucose cotransporter that uses ion gradients to drive active transport of nutrients, neurotransmitters, osmolytes and ions. It interacts with TNF-α, programmed cell death 1 (PDCD1) and complement component 4 (C4) and may induce apoptosis via the TNF-α - PDCD1 pathway. The gene encoding for this transporter also acts as an autoimmune modifier gene.
Sequence
Synthetic peptide located within the following region: VGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGVL
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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L-J Tsai et al.
Tissue antigens, 71(2), 114-126 (2007-12-12)
Genetic studies in several human autoimmune diseases suggest that the pericentromeric region of chromosome 16 might harbor an autoimmune modifier gene. We hypothesized that the sodium-dependent glucose cotransporter gene SLC5A11 is such a gene, and so might interact with immune-related
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