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AV32561

Sigma-Aldrich

Anti-FOXD3 antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Anti-Forkhead box D3
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

48 kDa

species reactivity

human, bovine, dog, rat, mouse

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FOXD3(27022)

General description

FOXD3 is a transcription factor that is involved in maintaining embryonic progenitors in mice. It inhibits interneuron suppression and activate neural crest cell-like phenotype.
Rabbit Anti-FOXD3 antibody recognizes canine, bovine, mouse, and human FOXD3.

Immunogen

Synthetic peptide directed towards the middle region of human FOXD3

Application

Rabbit Anti-FOXD3 antibody can be used for western blot applications at a concentration of 2.5μg/ml.

Biochem/physiol Actions

FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined.

Sequence

Synthetic peptide located within the following region: GAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYA

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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M Dottori et al.
Development (Cambridge, England), 128(21), 4127-4138 (2001-10-31)
The neural crest is a migratory cell population that gives rise to multiple cell types in the vertebrate embryo. The intrinsic determinants that segregate neural crest cells from multipotential dorsal progenitors within the neural tube are poorly defined. In this
Lynn A Hanna et al.
Genes & development, 16(20), 2650-2661 (2002-10-17)
Critical to our understanding of the developmental potential of stem cells and subsequent control of their differentiation in vitro and in vivo is a thorough understanding of the genes that control stem cell fate. Here, we report that Foxd3, a

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