AV31622
Anti-SP7 antibody produced in rabbit
affinity isolated antibody
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All Photos(3)
Synonym(s):
Anti-Sp7 transcription factor
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
45 kDa
species reactivity
human, bovine
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SP7(121340)
General description
SP7 is a zinc-finger containing transcription factor that regulates BMP6-induced osteoblast differentiation.
Rabbit Anti-SP7 antibody recognizes bovine, human, mouse, and rat SP7.
Rabbit Anti-SP7 antibody recognizes bovine, human, mouse, and rat SP7.
Immunogen
Synthetic peptide directed towards the C terminal region of human SP7
Application
Rabbit Anti-SP7 antibody is suitable for use in western blot (0.125μg/ml) and immunohistochemical (4-8μg/ml) assays.
Biochem/physiol Actions
SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation.
Sequence
Synthetic peptide located within the following region: RTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSP
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Fengchang Zhu et al.
Journal of cellular physiology, 227(6), 2677-2685 (2011-09-08)
The transcription factor osterix (Sp7) is essential for osteoblastogenesis and bone formation in mice. Genome wide association studies have demonstrated that osterix is associated with bone mineral density in humans; however, the molecular significance of osterix in human osteoblast differentiation
Xiao-Tao He et al.
Journal of cellular and molecular medicine, 22(2), 1302-1315 (2017-11-07)
Macrophages (Mφs) are involved in a variety of physiological and pathological events including wound healing and tissue regeneration, in which they play both positive and negative roles depending on their polarization state. In this study, we investigated the cellular behaviours
Ting Wang et al.
Phytotherapy research : PTR, 33(4), 1074-1083 (2019-02-16)
Osteoporosis is characterized by low bone mineral density and microarchitectural deterioration of bone tissue. N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (MBOC) is one of the macamides isolated from Maca (Lepidium meyenii Walp.), a cruciferous plant from the Andes of Peru. In this study, C3H/10T1/2 mesenchymal
Ting Wang et al.
Phytotherapy research : PTR, 33(4), 1074-1083 (2019-02-16)
Osteoporosis is characterized by low bone mineral density and microarchitectural deterioration of bone tissue. N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (MBOC) is one of the macamides isolated from Maca (Lepidium meyenii Walp.), a cruciferous plant from the Andes of Peru. In this study, C3H/10T1/2 mesenchymal
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