AV31443
Anti-HHEX antibody produced in rabbit
affinity isolated antibody
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Anti-Hematopoietically expressed homeobox
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
30 kDa
species reactivity
human, horse, rat, dog
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HHEX(3087)
General description
HHEX is a homeobox protein that is involved in developmental functions. HHEX variations have been identified as risk factors for diabetes type 2 in Japanese population groups.
Rabbit Anti-HHEX antibody recognizes pig, human, canine, bovine, mouse, and rat HHEX.
Rabbit Anti-HHEX antibody recognizes pig, human, canine, bovine, mouse, and rat HHEX.
Immunogen
Synthetic peptide directed towards the middle region of human HHEX
Application
Rabbit Anti-HHEX antibody is suitable for use in western blot (0.5μg/ml) and immunohistochemistry (4-8μg/ml) applications.
Biochem/physiol Actions
HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
Sequence
Synthetic peptide located within the following region: KQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQED
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Diabetologia, 50(12), 2461-2466 (2007-10-12)
Recently, several groups have carried out whole-genome association studies in European and European-origin populations and found novel type 2 diabetes-susceptibility genes, fat mass and obesity associated (FTO), solute carrier family 30 (zinc transporter), member 8 (SLC30A8), haematopoietically expressed homeobox (HHEX)
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