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APREST72771

Sigma-Aldrich

PrEST Antigen P2RY12

Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution

Synonym(s):

HORK3, P2Y12, SP1999

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About This Item

UNSPSC Code:
12352202

recombinant

expressed in E. coli

Assay

>80% (SDS-PAGE)

form

buffered aqueous solution

mol wt

predicted mol wt 22 kDa

purified by

immobilized metal affinity chromatography (IMAC)

concentration

≥0.5 mg/mL

immunogen sequence

KSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM

Ensembl | human accession no.

ENSG00000169313

UniProt accession no.

Q9H244

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... P2RY12(64805)

General description

Recombinant protein fragment of Human P2RY12 with N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G) fusion tag.

Application

Suitable as a blocking agent using corresponding antibodies.

Linkage

Corresponding Antibody HPA014518.

Physical form

Solution in 1 M urea-PBS, pH 7.4

Preparation Note

The protein solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.

Legal Information

Prestige Antigens is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
000054195
000053975
000032311

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Alexander Mildner et al.
Glia, 65(2), 375-387 (2016-11-20)
Microglia are resident immune cells in the central nervous system (CNS), which are essential for immune defence and critically contribute to neuronal functions during homeostasis. Until now, little is known about microglia biology in humans in part due to the

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