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A9920

β-Alanine

Name: β-Alanine
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:

NH₂CH₂CH₂COOH

CAS Number:

107-95-9

Molecular Weight:

89.09

Beilstein:

906793

EC Number:

203-536-5

MDL number:

MFCD00008200

UNSPSC Code:

12352209

eCl@ss:

39030936

PubChem Substance ID:

24891409

NACRES:

NA.75

product line

BioReagent

Quality Level

200

Assay

≥98% (TLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

202 °C (dec.) (lit.)

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Amino Acids

General description

An N-blocked form of alanine.

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Stroke prevention in atrial fibrillation patients with chronic kidney disease.

Robert G Hart et al.

The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)

Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate

Meta-analysis of randomized controlled trials on risk of myocardial infarction from the use of oral direct thrombin inhibitors.

Ramin Artang et al.

The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)

Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a

Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase.

K M Gibson et al.

Journal of neurochemistry, 81(1), 71-79 (2002-06-18)

Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting

Routine coagulation assays underestimate levels of antithrombin-dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis.

Wilma Potze et al.

British journal of haematology, 163(5), 666-673 (2013-11-14)

There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these patients is rapidly emerging. Due to extensive haemostatic changes in patients with cirrhosis, careful monitoring of anticoagulant therapy may be

Production of compartmented cultures of rat sympathetic neurons.

Robert B Campenot et al.

Nature protocols, 4(12), 1869-1887 (2009-12-17)

The compartmented culture, in which primary neurons plated in a proximal compartment send their axons under silicone grease barriers and into left and right distal compartments, has enhanced the experimental capabilities of neuronal cultures. Treatments can be applied separately to

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β-Alanine in Cell Culture

Learn more about β-Alanine, an important amino acid supplement and explore how it is used in cell culture. We offer a comprehensive portfolio of amino acid cell culture supplements and reagents.

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