A9484
Anti-AIF1 (72-84) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Synonym(s):
Anti-Allograft inflammatory factor 1 isoform 1, Anti-IBA1, Anti-IRT-1
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~10 kDa
species reactivity
human
technique(s)
western blot: 1:500-1:2,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... AIF1(199)
General description
Allograft inflammatory factor-1 (AIF-1) is a vascular smooth muscle cells (VSMC) protein that is induced during allograft and angioplasty injury. Studies have reported that AIF-1 can polymerize actin, stimulate Rac1 and facilitate the migration of VSMCs.
Rabbit Anti-AIF1 (72-84) antibody binds to amino acids 72-84 of human AIF1.
Rabbit Anti-AIF1 (72-84) antibody binds to amino acids 72-84 of human AIF1.
Immunogen
synthetic peptide corresponding to amino acids 72-84 of human AIF1
Application
Immunoflourescence was performed on cyrosectioned mouse retinas using rabbit anti-AIF1 antibody as the primary. Anti-AIF1 labeled photoreceptor segments and the outer plexiform layer.
Rabbit Anti-AIF1 (72-84) antibody can be used for western blot applications at dilutions ranging from 1:500 to 1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Hans G Novrup et al.
Journal of neuroinflammation, 11, 159-159 (2014-09-11)
Glial cell activation and overproduction of inflammatory mediators in the central nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, including spinal cord injury (SCI). Elevated levels of the proinflammatory cytokine tumor necrosis factor (TNF), which
Elysse M Knight et al.
Neurobiology of aging, 35(8), 1821-1832 (2014-03-19)
Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive deficits in AD mouse models. However, the effect of a high-fat diet on
Michael V Autieri et al.
Circulation research, 92(10), 1107-1114 (2003-04-26)
Development of vascular restenosis is a multifaceted process characterized by migration and proliferation of vascular smooth muscle cells (VSMCs), resulting in loss of lumen diameter. Characterization of proteins that mediate this process is essential in our understanding of the pathogenesis
Takehito Imamura et al.
European journal of obstetrics, gynecology, and reproductive biology, 180, 16-23 (2014-07-14)
Human heat shock protein 70 (HSP70) has been reported to enhance Toll-like receptor 4-mediated pelvic inflammation and growth of endometriotic cells. However, information on tissue expression of HSP70 before and after treatment with estrogen suppressing agent is scanty. Here, we
Anna Klinke et al.
American journal of respiratory cell and molecular biology, 51(1), 155-162 (2014-02-14)
Pulmonary arterial hypertension (PAH) is characterized by adverse remodeling of pulmonary arteries. Although the origin of the disease and its underlying pathophysiology remain incompletely understood, inflammation has been identified as a central mediator of disease progression. Oxidative inflammatory conditions support
Related Content
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service