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A9256

Sigma-Aldrich

L-Aspartic acid

≥98% (HPLC)

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Synonym(s):
(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid
Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
133.10
Beilstein:
1723530
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

Assay

≥98% (HPLC)

form

powder, crystals or chunks

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

H2O: 5 mg/mL
0.5 M HCl: 50 mg/mL (with heat)
1 M NaOH: 50 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

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Application

L-aspartic acid has been used as one of the components of synthetic drop out media for culturing budding yeast. It has also been used to study non-enzymatic gluconeogenesis.

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.
Aspartic acid is a non-essential amino acid. It is involved in the Urea cycle, Krebs cycle and in DNA metabolism.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Messner CB
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Mitochondrial dysfunction is associated with activation of the integrated stress response (ISR) but the underlying triggers remain unclear. We systematically combined acute mitochondrial inhibitors with genetic tools for compartment-specific NADH oxidation to trace mechanisms linking different forms of mitochondrial dysfunction

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