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A7003

Sigma-Aldrich

Alginic acid from brown algae

powder

Synonym(s):

Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid

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About This Item

Linear Formula:
(C6H8O6)n
CAS Number:
9005-32-7
EC Number:
232-680-1
MDL number:
MFCD00081309
UNSPSC Code:
12171500
NACRES:
NA.47

form

powder

Quality Level

200

technique(s)

titration: suitable

color

white to light yellow

pH range

1.5-3.5

mp

300 °C

solubility

H2O: insoluble, but swells
aqueous base: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

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General description

Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae. It is reported to inhibit the reverse transcriptase activity of HIV. Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported. Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported. Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported. It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).

Application

Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.

Other Notes

A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000399352
0000401399
0000382762
0000311422
0000311423

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C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component
In situ, real-time FT-IR/CIR/ATR study of the biocorrosion of copper by gum arabic, alginic acid, bacterial culture supernatant and Pseudomonas atlantica exopolymer.
Jolley JG, et al.
Applied Spectroscopy, 43(6), 1062-1067 (1989)
A dye-binding assay for the spectrophotometric measurement of transparent exopolymer particles (TEP).
Passow U and Alldredge AL.
Limnology and Oceanography, 40(7), 1326-1335 (1995)
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