A6757
D-Arginine monohydrochloride
≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
210.66
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-010-1
MDL number:
Beilstein/REAXYS Number:
5773432
Product Name
D-Arginine monohydrochloride, ≥98% (TLC)
InChI key
KWTQSFXGGICVPE-PGMHMLKASA-N
InChI
1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m1./s1
SMILES string
Cl.N[C@H](CCCNC(N)=N)C(O)=O
assay
≥98% (TLC)
form
powder
color
white
mp
216-218 °C
application(s)
cell analysis
peptide synthesis
Quality Level
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Application
D-arginine attenuates increased arginase expression, oxidative stress, endothelial dysfunction, and advanced glycation endproducts formation induced by methylgloxyl and high glucose. This attenuation by D-arginine is thought to occur through an endothelial NOS independent mechanism.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Phuong V Tran et al.
Biochemical and biophysical research communications, 533(4), 965-970 (2020-10-04)
Central administration of L-arginine was reported to attenuate stress responses in neonatal chicks. The present study aimed to elucidate the differential effects of centrally administered L-arginine and its enantiomer, D-arginine, on the stress response in chicks and the associated mechanisms.
D-arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an eNOS-independent mechanism
Dahr, I., et al.
Journal of Pharmacology and Experimental Therapeutics, 63, 196-204 (2012)
A simple method of preparing D-(minus)-arginine monohydrochloride from DL-arginine.
C P Berg et al.
Analytical biochemistry, 63(1), 68-72 (1975-01-01)
Ruo-Xiao Cheng et al.
Theranostics, 9(15), 4287-4307 (2019-07-10)
Methylglyoxal (MGO), an endogenous reactive carbonyl compound, plays a key role in the pathogenesis of diabetic neuropathy. The aim of this study is to investigate the role of MGO in diabetic itch and hypoalgesia, two common symptoms associated with diabetic
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