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A6683

Sigma-Aldrich

L-Aspartic acid sodium salt monohydrate

≥98% (TLC)

Synonym(s):

(S)-2-Aminobutanedioic acid sodium salt, Sodium L-aspartate

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About This Item

Linear Formula:
HO2CCH2CH(NH2)CO2Na · H2O
CAS Number:
323194-76-9
Molecular Weight:
173.10
Beilstein:
6101944
EC Number:
223-264-0
MDL number:
MFCD00152960
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24891129
NACRES:
NA.32

product name

L-Aspartic acid sodium salt monohydrate, ≥98% (TLC)

Quality Level

200

Assay

≥98% (TLC)

form

powder

color

white

SMILES string

[Na+].[H]O[H].N[C@@H](CC(O)=O)C([O-])=O

InChI

1S/C4H7NO4.Na.H2O/c5-2(4(8)9)1-3(6)7;;/h2H,1,5H2,(H,6,7)(H,8,9);;1H2/q;+1;/p-1/t2-;;/m0../s1

InChI key

PPTHNBYUFXSJPS-JIZZDEOASA-M

Gene Information

human ... GRIN2A(2903)
rat ... GRIN2A(14811)

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General description

Aspartic acid is a non-essential amino acid. L-Aspartic acid is a dicarboxylic amino acid, which is involved in the synthesis of nerve cells proteins. It also stimulates the depolarization of nerve cell membranes. L-Aspartic acid acts as an amine donor for transamination reaction.

Application

L-Aspartic acid sodium salt monohydrate has been as a component of reservoir solution for crystallization.

Biochem/physiol Actions

Selective outflow of L-aspartic acid across the blood-brain barrier controls the level of L and D aspartic acid in the brain. Increased levels of L-aspartic acid in the brain results in excitatory neurotoxicity. Recent studies highlight that racemization of L-aspartic acid is followed by the determination of D:L ratio to estimate the age of an individual.
Principal neurotransmitter for fast synaptic excitation.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Structural insight into substrate selectivity of Erwinia chrysanthemi l-Asparaginase
Nguyen HA, et al.
Biochemistry, 55(8), 1246-1253 (2016)
The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood?brain barrier
Kazuhiro Tetsuka
Journal of Neurochemistry, 87(4), 891-901 (2003)
Age estimation of living Indian individuals based on aspartic acid racemization from tooth biopsy specimen
Manu Rastogi
Journal of Forensic Sciences, 9(2), 83-90 (2017)
Molecular interactions of some non-essential amino acids in aqueous solutions of 1-methylimidazolium chloride at different temperatures
Gaba R, et al.
Journal of Molecular Liquids (2019)
The Biological Effects of Glutamic Acid and Its Derivatives (2012)
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