A6582
Antifoam A concentrate
active silicone polymer 100%
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UNSPSC Code:
12161901
NACRES:
NA.85
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Quality Level
form
emulsion (aqueous)
technique(s)
cell culture | hybridoma: suitable
microbiological culture: suitable
density
0.97 g/mL at 25 °C
application(s)
microbiology
storage temp.
room temp
suitability
(Mammalian (suspension))
bacteria (fermentation)
Related Categories
General description
Antifoam A is a silicone-based product used to prevent or minimize foaming in both microbial fermentation systems and mammalian suspension cultures. Control of foaming minimizes damage to the cells, resulting in increased protein/antibody production. Extremely effective for aqueous and non-aqueous systems. Effective at concentrations in the 1-50ppm range.
Application
Antifoam A concentrate has been used:
- in bioreactor culture for Staphylococcal enterotoxin C (SEC) production.
- to prevent foam formation during the aerobic treatment of sludge.
- to study the impact of surface tension on bioaerosol generation during bubbling.
Features and Benefits
- Molecular biology grade and tested for use in bacterial fermentation.
- Extremely effective foam suppressor for aqueous and non-aqueous systems.
- Made of 100% active silicone polymer, free of emulsifiers.
- Typically, effective at 1-100 ppm.
- Product will be stable in the pH range of 5 to 9.
- Can be directly added to a fermentation medium but it is not recommended that it be pumped to a fermenter on an as-needed basis.
Components
Antifoam A is a 100% active silicon polymer containing no non-ionic emulsifiers .
Preparation Note
Antifoam A can be pre-diluted with 3-10 parts of aqueous propylene glycol or non-aqueous vegetable oil with slow mixing.
related product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
WGK
WGK 3
Flash Point(F)
>213.8 °F
Flash Point(C)
> 101 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Experience with a perfo-suction system for the recovery of schistosomes from laboratory rodents
T. F. H. G. Jackson, C. D. Dettman, et al.
Laboratory Animal Science, 16, 65-67 (1982)
The biodegradability of aquatic worm predated waste activated sludge: A sequential aerobic and anaerobic treatment approach
de Valk S, et al.
bioresource technology reports, 12.0, 100606-100606 (2020)
Bioaerosol Release from Concentrated Microbial Suspensions in Bubbling Processes
Kruglyakova E, et al.
Air quality, atmosphere, & health, 13.0, 2029-2029 (2022)
Factors affecting staphylococcal enterotoxin C bovine production in milk
Hunt K, et al.
International dairy journal, 39(1), 41-46 (2014)
M Schlömann et al.
Journal of bacteriology, 172(9), 5119-5129 (1990-09-01)
Enzymatic conversion of 4-fluorocatechol in the simultaneous presence of partially purified preparations of catechol 1,2-dioxygenase from Pseudomonas cepacia and muconate cycloisomerase from Alcaligenes eutrophus 335 yielded a product that was unambiguously identified as (+)-4-fluoromuconolactone [(+)-4-carboxymethyl-4-fluoro-but-2-en-4-olide]. This compound was shown to
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