A6508
L-Aspartic acid β-hydroxamate
>98%
Synonym(s):
AAH, HDX, LAH
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About This Item
Empirical Formula (Hill Notation):
C4H8N2O4
CAS Number:
Molecular Weight:
148.12
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
L-Aspartic acid β-hydroxamate, serine racemase inhibitor
SMILES string
N[C@@H](CC(=O)NO)C(O)=O
InChI
1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
ZBYVTTSIVDYQSO-REOHCLBHSA-N
assay
>98%
form
powder
color
white to yellow
application(s)
detection
storage temp.
−20°C
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Franck Danel et al.
Current drug discovery technologies, 8(1), 66-75 (2010-11-26)
Aminoacyl-tRNA synthetases (AARSs) are a structurally heterogeneous family of enzymes present in prokaryotes, archaea and eukaryotes. They catalyze the attachment of tRNA to its corresponding amino acid via an aminoacyl adenylate intermediate. Errors in protein synthesis will occur if an
N Thomasset et al.
International journal of cancer, 49(3), 421-424 (1991-09-30)
D and L isomers of aspartic acid beta-hydroxamate (respectively DAH and LAH) were compared for their in vitro and in vivo activity against the murine leukemia L5178Y and their tolerance in vivo in DBA/2 mice. DAH and LAH displayed comparable
Eric R. Braverman
The Healing Nutrients Within: Facts, Findings, and New Research on Amino Acids null
Noam Nissan et al.
Journal of magnetic resonance imaging : JMRI, 49(2), 508-517 (2018-09-01)
Pregnancy-associated breast cancer (PABC) is often a delayed diagnosis and contrast-enhanced MRI is contraindicated because gadolinium agents are known to cross the placenta. To investigate the feasibility and clinical utility of noncontrast breast MRI using diffusion tensor imaging (DTI) in
Yujiao Zhou et al.
Journal of immunology research, 2018, 9832467-9832467 (2018-08-18)
Dendritic cells (DCs) harboring tumor-associated antigen are supposed to be a potential immunotherapy for hepatocellular carcinoma (HCC). Aspartate-β-hydroxylase (AAH), an overexpressed tumor-associated cell surface protein, is considered as a promising biomarker and therapeutic target for HCC. In this study, we
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