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A6161

Sigma-Aldrich

4-Aminophenol hydrochloride

powder

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Synonym(s):
4-Hydroxyaniline hydrochloride
Linear Formula:
H2NC6H4OH · HCl
CAS Number:
51-78-5
Molecular Weight:
145.59
Beilstein:
3911747
EC Number:
200-122-6
MDL number:
MFCD00012996
UNSPSC Code:
12352200
PubChem Substance ID:
24891061
NACRES:
NA.25

form

powder

color

gray

mp

300-305 °C (dec.) (lit.)

SMILES string

Cl[H].Nc1ccc(O)cc1

InChI

1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H

InChI key

RVGOBWDGAVAVPJ-UHFFFAOYSA-N

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Application

4-Aminophenol (p-aminophenol, PAP), a nephrotoxin and hepatotoxin, may be used to study its mechanisms of biological toxicity and glutathione depletion.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Mohammad Mahdi Najafpour et al.
Dalton transactions (Cambridge, England : 2003), 41(14), 3906-3910 (2012-02-14)
We describe here the ability of manganese oxide monosheets to aggregate to form layered structures with 4-aminophenol molecules. These aggregated monosheets could be considered as the first step to synthesize a self-assembled layered hybrid of phenol-manganese ions with phenol and
Abilash Gangula et al.
Langmuir : the ACS journal of surfaces and colloids, 27(24), 15268-15274 (2011-10-27)
A simple, green method is described for the synthesis of Gold (Au) and Silver (Ag) nanoparticles (NPs) from the stem extract of Breynia rhamnoides. Unlike other biological methods for NP synthesis, the uniqueness of our method lies in its fast
Waqas Khalid et al.
Journal of nanobiotechnology, 9, 46-46 (2011-10-11)
An electrochemical sensor for p-aminophenyl phosphate (pAPP) is reported. It is based on the electrochemical conversion of 4-aminophenol (4AP) at a quantum dot (QD) modified electrode under illumination. Without illumination no electron transfer and thus no oxidation of 4AP can
Yanpeng Xue et al.
Journal of colloid and interface science, 379(1), 89-93 (2012-05-23)
In this study, a facile one-step redox polymerization method for the preparation of highly dispersed palladium (Pd)/polypyrrole (PPy) nanocapsules has been demonstrated. During the polymerizaion process, the formation of RB-PdCl(4)(2-) complex via an electrostatic interaction plays a key role for
Annette John-Baptiste et al.
International journal of toxicology, 31(6), 529-536 (2012-11-03)
Kidney injury biomarkers have been utilized by pharmaceutical companies as a means to assess the potential of candidate drugs to induce nephrotoxicity. Multiple platforms and assay methods exist, but the comparison of these methods has not been described. Millipore's Kidney
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