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Safety Information

A6161

Sigma-Aldrich

4-Aminophenol hydrochloride

powder

Synonym(s):

4-Hydroxyaniline hydrochloride

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About This Item

Linear Formula:
H2NC6H4OH · HCl
CAS Number:
51-78-5
Molecular Weight:
145.59
Beilstein:
3911747
EC Number:
200-122-6
MDL number:
MFCD00012996
UNSPSC Code:
12352107
PubChem Substance ID:
24891061
NACRES:
NA.25

form

powder

color

gray

mp

300-305 °C (dec.) (lit.)

SMILES string

Cl[H].Nc1ccc(O)cc1

InChI

1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H

InChI key

RVGOBWDGAVAVPJ-UHFFFAOYSA-N

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Application

4-Aminophenol (p-aminophenol, PAP), a nephrotoxin and hepatotoxin, may be used to study its mechanisms of biological toxicity and glutathione depletion.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBF4840V
1363519V
BCBF4441V
1363519
1332318

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Yuko Ueno et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 29(1), 55-60 (2013-01-11)
We have developed a new procedure for fabricating interdigitated array gold electrodes (Au-IDA) modified with reduced graphene oxide (rGO). In this procedure, we coated the gold surface of the micrometer order electrodes with graphene oxide (GO) prior to the reduction
Leandro Yoshio Shiroma et al.
Analytica chimica acta, 725, 44-50 (2012-04-17)
The present work describes the construction and application of a simple, low cost and sensitive microfluidic paper-based device with electrochemical detection for the detection of paracetamol and 4-aminophenol. The separation channels of a width of 2.0 mm were created on
Tomoyuki Yasukawa et al.
Biosensors & bioelectronics, 37(1), 19-23 (2012-05-23)
In this work, a novel immunosensing method has been developed on the basis of the sensitive determination of a product generated by an enzyme reaction with dual amplification system combining an electrochemical-redox cycling and coulometric signal transduction using a galvanic
Rosivaldo S Borges et al.
Chemical biology & drug design, 81(3), 414-419 (2013-02-15)
This theoretical and experimental study describes the design and evaluation of the free-radical scavenging effect for the molecular association of 4-aminophenol and salicylate derivatives. For this purpose, we employed theoretical methods for the selection of antioxidant drugs and the rapid
Hyeok-Jin Ko et al.
Biotechnology letters, 34(4), 677-682 (2011-12-02)
Aryl acylamidase (EC 3.5.1.13, AAA) acts on the amide bond between aryl and acyl groups. Whole cells of Escherichia coli overexpressing a novel bacterial AAA synthesized p-acetaminophenol (p-AAP) from p-aminophenol (p-AP, aryl compound) and acetate (acyl donor). Optimum conditions were
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