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Synonym(s):
Calmodulin−Agarose, Phosphodiesterase 3′,5′-Cyclic Nucleotide Activator-Agarose from bovine testes
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biological source
Saccharomyces cerevisiae
Quality Level
form
saline suspension
extent of labeling
≥0.5 mg per mL
technique(s)
affinity chromatography: suitable
matrix
4% beaded agarose
matrix activation
cyanogen bromide
matrix attachment
amino
matrix spacer
1 atom
suitability
suitable for chromatography
storage temp.
2-8°C
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Application
Calmodulin-agarose is used in affinity chromatography, protein chromatography, calcium associated proteins, and specialty resins. Calmodulin-agarose has been used to suggest a coordinated regulation of processes in both mitochondria and chloroplasts by calcium signals. Calmodulin-agarose has also been used to study apoptosis in prostate cancer cells and to analyze the interaction of the influenza virus polymerase complex with human cell factors.
Physical form
Suspension in 0.5 M NaCl containing preservative
WGK
WGK 3
Regulatory Information
动植物源性产品
Certificates of Analysis (COA)
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Ninghai Gan et al.
Nature, 572(7769), 387-391 (2019-07-23)
The bacterial pathogen Legionella pneumophila creates an intracellular niche permissive for its replication by extensively modulating host-cell functions using hundreds of effector proteins delivered by its Dot/Icm secretion system1. Among these, members of the SidE family (SidEs) regulate several cellular
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