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Merck
CN

A5754

3-Amino-9-ethylcarbazole

≥95% (HPLC), powder

Synonym(s):

9-Ethylcarbazol-3-amine, AEC

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About This Item

Empirical Formula (Hill Notation):
C14H14N2
CAS Number:
132-32-1
Molecular Weight:
210.27
NACRES:
NA.83
PubChem Substance ID:
24891017
UNSPSC Code:
12352204
MDL number:
MFCD00004964
Beilstein/REAXYS Number:
174969

Key Documents

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Product Name

3-Amino-9-ethylcarbazole, ≥95% (HPLC), powder

form

powder

InChI

1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3

SMILES string

CCn1c2ccccc2c3cc(N)ccc13

InChI key

OXEUETBFKVCRNP-UHFFFAOYSA-N

assay

≥95% (HPLC)

impurities

≤3% solvent

solubility

ethanol: acetic acid (2:1): 50 mg/mL, clear to hazy

storage temp.

2-8°C

Quality Level

200

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Analysis Note

Actual content given on label

Application

3-Amino-9-ethylcarbazole has been used to visualize the bound primary antibody by using a streptavidin method. It has also been used in visualizing tissue sections from tumour samples.

Biochem/physiol Actions

3-Amino-9-ethylcarbazole is a peroxidase substrate suitable for use in immunoblotting and immunohistochemical staining procedures. This substrate produces an insoluble end product that is red in color and can be observed visually.

General description

3-Amino-9-ethylcarbazole serves as chromogen in immunocytochemistry and produces a red color.
Substrate for peroxidase.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H301,H350

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000501656
0000501656
0000499374
0000499373
0000499373

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VEGF-C and COX-2 expression in papillary thyroid cancer
Siironen P, et al.
Endocrine-Related Cancer, 13(2), 465-473 (2006)
Patterns of angiogenesis in nonsmall-cell lung carcinoma
Offersen BV, et al.
Cancer, 91(8), 1500-1509 (2001)
Viktor H Koelzer et al.
Translational research : the journal of laboratory and clinical medicine, 166(2), 207-217 (2015-03-24)
Tumor budding (single tumor cells or small tumor cell clusters) at the invasion front of colorectal cancer (CRC) is an adverse prognostic indicator linked to epithelial-mesenchymal transition. This study characterized the immunogenicity of tumor buds by analyzing the expression of
Rihab Bouchareb et al.
Circulation, 132(8), 677-690 (2015-08-01)
Mendelian randomization studies have highlighted that lipoprotein(a) [Lp(a)] was associated with calcific aortic valve disease (CAVD). Lp(a) transports oxidized phospholipids with a high content in lysophosphatidylcholine. Autotaxin (ATX) transforms lysophosphatidylcholine into lysophosphatidic acid. We hypothesized that ATX-lysophosphatidic acid could promote
Veronika Mlitz et al.
The Journal of investigative dermatology, 134(11), 2685-2692 (2014-05-02)
S100 fused-type proteins (SFTPs) such as filaggrin, trichohyalin, and cornulin are differentially expressed in cornifying keratinocytes of the epidermis and various skin appendages. To determine evolutionarily conserved, and thus presumably important, features of SFTPs, we characterized nonmammalian SFTPs and compared
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